hCG (10000 iu)
Part 1: How to Mix (Reconstitute 10000 iu vial)
- Add 2 mL (200 units) of bacteriostatic water to your 10,000 iu hCG vial.
- Slowly push the needle into the powder vial. Aim the needle at the glass wall and press the plunger slowly so the water trickles down.
- Dissolve: Gently swirl the vial in circles until the liquid is completely clear. Do not shake it like a cocktail shaker, as rough shaking can damage the hormone.
- Store: Put the mixed vial straight into the refrigerator. It must stay cold.
Part 2: Dosing & Schedule (Option A: 250 iu Dose)
- Dose 5 units 3 times a week. Here is exactly how much hCG you get in that single 5-unit dose:
- hCG: 250 iu
Part 3: How Long It Lasts (Option A)
- Total Liquid: 2.0 mL = 200 units total.
- Your Dose: 5 units out of 200 units means you are taking exactly 2.5% of the vial per dose.
- Vial Lifespan: This setup gives you exactly 40 total doses per 10,000 iu vial.
- 1 Vial lasts 13.3 weeks (approx. 3 months) when following a schedule of 3 days a week.
Part 2: Dosing & Schedule (Option B: 500 iu Dose)
- Dose 10 units 3 times a week. Here is exactly how much hCG you get in that single 10-unit dose:
- hCG: 500 iu
Part 3: How Long It Lasts (Option B)
- Total Liquid: 2.0 mL = 200 units total.
- Your Dose: 10 units out of 200 units means you are taking exactly 5% of the vial per dose.
- Vial Lifespan: This setup gives you exactly 20 total doses per 10,000 iu vial.
- 1 Vial lasts 6.6 weeks (approx. 1.5 months) when following a schedule of 3 days a week.
hCG (5000 iu)
Part 1: How to Mix (Reconstitute 5000 iu vial)
- Add 1 mL (100 units) of bacteriostatic water to your 5,000 iu hCG vial.
- Slowly push the needle into the powder vial. Aim the needle at the glass wall and press the plunger slowly so the water trickles down.
- Dissolve: Gently swirl the vial in circles until the liquid is completely clear. Do not shake it like a cocktail shaker, as rough shaking can damage the hormone.
- Store: Put the mixed vial straight into the refrigerator. It must stay cold.
Part 2: Dosing & Schedule (Option A: 250 iu Dose)
- Dose 5 units 3 times a week. Here is exactly how much hCG you get in that single 5-unit dose:
- hCG: 250 iu
Part 3: How Long It Lasts (Option A)
- Total Liquid: 1.0 mL = 100 units total.
- Your Dose: 5 units out of 100 units means you are taking exactly 5% of the vial per dose.
- Vial Lifespan: This setup gives you exactly 20 total doses per 5,000 iu vial.
- 1 Vial lasts 6.6 weeks (approx. 1.5 months) when following a schedule of 3 days a week.
Part 2: Dosing & Schedule (Option B: 500 iu Dose)
- Dose 10 units 3 times a week. Here is exactly how much hCG you get in that single 10-unit dose:
- hCG: 500 iu
Part 3: How Long It Lasts (Option B)
- Total Liquid: 1.0 mL = 100 units total.
- Your Dose: 10 units out of 100 units means you are taking exactly 10% of the vial per dose.
- Vial Lifespan: This setup gives you exactly 10 total doses per 5,000 iu vial.
- 1 Vial lasts 3.3 weeks when following a schedule of 3 days a week.
Peptide dosing and reconstitution requirements vary significantly from person to person based on individual biology, weight, and research goals. All guides, charts, and protocol baselines provided by Amino-pedia are intended strictly for general educational purposes within the research community. It is the sole responsibility of the individual to conduct thorough due diligence and determine what protocols are safe and appropriate for their specific needs. Amino-pedia assumes no responsibility or liability for individual research outcomes or safety.
1. Zinc (with Copper)
hCG directly signals the Leydig cells in your testes to produce testosterone, which subsequently increases the rate of aromatization into estrogen. Zinc acts as a natural, mild aromatase modulator.
- Why It Pairs: Zinc helps inhibit the aromatase enzyme to prevent excessive estrogen spikes, while simultaneously supporting healthy sperm maturation and motility (perfectly aligning with hCG’s fertility-preserving goals). Pairing it with a tiny amount of copper prevents a zinc-induced copper deficiency.

Pure Encapsulations Zinc 30 mg – Supplement for Immune System Support, Growth and Development, and Wound Healing* – with Zinc Picolinate 30 mg – 180 Capsules
2. DIM (Diindolylmethane) or Calcium D-Glucarate
Because hCG causes a direct, localized pulse of testicular estrogen production, managing how your liver processes and excretes these estrogen metabolites is highly beneficial.
- Why It Pairs: DIM helps convert strong, highly active estrogens into weaker, safer metabolites. Calcium D-Glucarate supports the liver’s glucuronidation pathway, ensuring that bound-up estrogen is successfully excreted from the body rather than reabsorbed in the gut. Together, they help prevent side effects like water retention or mood swings.

Pure Encapsulations DIM Detox | Supplement Support for Detoxification and Cellular Health* | 60 Capsules
3. Omega-3 Fatty Acids (High EPA/DHA)
Hormone optimization protocols can sometimes put stress on your lipid profiles or lead to a slight thickening of the blood (elevated hematocrit).
- Why It Pairs: Omega-3 fatty acids act as a natural blood thinner to help maintain ideal blood viscosity, while supporting cardiovascular health, improving joint lubrication, and keeping your cholesterol/triglyceride ratios in a healthy range.

Pure Encapsulations EPA/DHA Essentials – Fish Oil Concentrate Supplement to Support Cardiovascular Health* – Premium EPA & DHA Supplement with Omega 3-90 Softgel Capsules
4. Vitamin D3 & K2
Vitamin D is a secosteroid hormone that plays a foundational role in cellular signaling, bone density, and endocrine health.
- Why It Pairs: Vitamin D supports the signaling pathways of both luteinizing hormone (LH) and the Leydig cells that hCG mimics. Adding Vitamin K2 ensures that the calcium absorbed by the high-dose Vitamin D is properly directed into your bones and teeth, rather than accumulating in your blood vessels.

Pure Encapsulations Vitamin D3 & K2 – Bone & Vascular Health Support – Immune Function* – Gluten Free – Non-GMO – 120 Capsules
